5TPW
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NMDA glutamate receptor subunit | polymer | 389 | 43546.7 | 1 | UniProt (Q91977) Pfam (PF01094) UniProt (by SIFTS) (A0A1L8F5J9) In PDB | Xenopus laevis (African clawed frog) | |
| 2 | B | Glutamate receptor ionotropic, NMDA 2A | polymer | 360 | 40572.1 | 1 | UniProt (Q00959) Pfam (PF01094) In PDB | Rattus norvegicus (Rat) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NR2A |
| 3 | H | FAB, HEAVY CHAIN | polymer | 221 | 23993.9 | 1 | Mus musculus | ||
| 4 | L | FAB, LIGHT CHAIN | polymer | 214 | 23568.0 | 1 | Mus musculus | ||
| 5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 24 - 408 (UniProt: Q91977)
| PDB | External Database | Details |
|---|---|---|
| Gln 61 | Asn 61 | engineered mutation |
| Gln 371 | Asn 371 | engineered mutation |
| Gly 409 | - | expression tag |
| Thr 410 | - | expression tag |
| Leu 411 | - | expression tag |
| Val 412 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131680.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1268.4 | |
| All* | Total formula weight | 132949.1 |
