5TPN
Crystal structure of RSV F in complex with human antibody hRSV90
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fusion glycoprotein F0,Fibritin | polymer | 510 | 56137.8 | 1 | UniProt (P03420) UniProt (Q38650) Pfam (PF00523) | Human respiratory syncytial virus A | Protein F |
| 2 | B (H) | hRSV90 heavy chain | polymer | 225 | 24236.0 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | hRSV0 light chain | polymer | 214 | 23302.8 | 1 | Homo sapiens (human) |
Sequence modifications
A: 27 - 513 (UniProt: P03420)
A: 518 - 544 (UniProt: Q38650)
| PDB | External Database | Details |
|---|---|---|
| Lys 66 | Glu 66 | conflict |
| Ile 67 | Asn 67 | engineered mutation |
| Ile 76 | Val 76 | conflict |
| Ala 102 | Pro 102 | conflict |
| Gln 128 | Arg 106 | conflict |
| - | Arg 109 | deletion |
| - | Glu 110 | deletion |
| - | Leu 111 | deletion |
| - | Pro 112 | deletion |
| - | Arg 113 | deletion |
| - | Phe 114 | deletion |
| - | Met 115 | deletion |
| - | Asn 116 | deletion |
| - | Tyr 117 | deletion |
| - | Thr 118 | deletion |
| - | Leu 119 | deletion |
| - | Asn 120 | deletion |
| - | Asn 121 | deletion |
| - | Ala 122 | deletion |
| - | Lys 123 | deletion |
| - | Lys 124 | deletion |
| - | Thr 125 | deletion |
| - | Asn 126 | deletion |
| - | Val 127 | deletion |
| - | Thr 128 | deletion |
| - | Leu 129 | deletion |
| - | Ser 130 | deletion |
| Gly 131 | Lys 131 | linker |
| Ser 132 | Lys 132 | linker |
| Gly 133 | Arg 133 | linker |
| Ser 134 | Lys 134 | linker |
| Gly 135 | Arg 135 | linker |
| Ser 137 | Phe 137 | conflict |
| Pro 215 | Ser 215 | engineered mutation |
| Val 379 | Ile 379 | engineered mutation |
| Val 447 | Met 447 | engineered mutation |
| Gln 487 | Glu 487 | conflict |
| Ser 514 | - | linker |
| Ala 515 | - | linker |
| Ile 516 | - | linker |
| Gly 517 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Val 548 | - | expression tag |
| Pro 549 | - | expression tag |
| Arg 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Ser 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103676.7 | |
| All* | Total formula weight | 103676.7 |
