5TPC
Binding domain of BoNT/A complexed with ganglioside
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Botulinum neurotoxin type A | polymer | 425 | 49680.2 | 1 | UniProt (P10845) Pfam (PF07953) Pfam (PF07951) UniProt (by SIFTS) (P0DPI1) In PDB | Clostridium botulinum | BoNT/A,Bontoxilysin-A,BOTOX |
| 2 | B | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 1 | In PDB GlyTouCan (G30207PZ) | |||
| 3 | C | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose | branched | 674.6 | 1 | In PDB GlyTouCan (G02684WR) | |||
| 4 | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 876 - 1296 (UniProt: P10845)
| PDB | External Database | Details |
|---|---|---|
| His 873 | - | expression tag |
| Met 874 | - | expression tag |
| Asp 875 | - | expression tag |
| Gln 1297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49680.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1146.0 | |
| All* | Total formula weight | 50826.2 |
