5TOT
Crystal structure of AAT H143L:H189L double mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aspartate aminotransferase, cytoplasmic | polymer | 414 | 46759.9 | 2 | UniProt (P00503) Pfam (PF00155) In PDB | Sus scrofa (Pig) | cAspAT,Cysteine aminotransferase,cytoplasmic,Cysteine transaminase,cCAT,Glutamate oxaloacetate transaminase 1,Transaminase A |
| 2 | water | water | 18.0 | 762 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 412 (UniProt: P00503)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Asn 63 | Asp 64 | conflict |
| Leu 143 | His 144 | engineered mutation |
| Leu 189 | His 190 | engineered mutation |
| Gln 288 | Glu 289 | conflict |
| Gln 376 | Glu 377 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93519.8 | |
| All* | Total formula weight | 93519.8 |
