5TOJ
Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Fusion glycoprotein F0, Fibritin chimera | polymer | 550 | 61045.0 | 3 | UniProt (P03420) Pfam (PF00523) In PDB | Human respiratory syncytial virus | Protein F |
| 2 | D, E, F | Single-domain antibody F-VHH-4 | polymer | 131 | 14437.0 | 3 | Lama glama (llama) | ||
| 3 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 513 (UniProt: P03420)
A, B, C: 514 - 550 (PDB: 5TOJ)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Pro 102 | conflict |
| Cys 155 | Ser 155 | engineered mutation |
| Phe 190 | Ser 190 | engineered mutation |
| Leu 207 | Val 207 | engineered mutation |
| Cys 290 | Ser 290 | engineered mutation |
| Val 379 | Ile 379 | engineered mutation |
| Val 447 | Met 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 226445.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 227109.5 |
