5TNH
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 17,18-EpETE hydrolysis intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, D, A, B) | CFTR inhibitory factor | polymer | 301 | 34163.7 | 4 | UniProt (A0A0M3KL26) Pfam (PF12697) UniProt (by SIFTS) (A0A0H2ZD27) | Pseudomonas aeruginosa (strain UCBPP-PA14) | |
| 2 | E, F, G, H (C, D, A, B) | (5Z,8Z,11Z,14Z,17R,18R)-17,18-dihydroxyicosa-5,8,11,14-tetraenoic acid | non-polymer | 336.5 | 4 | Chemie (7MS) | |||
| 3 | I, J, K, L (C, D, A, B) | water | water | 18.0 | 600 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 25 - 325 (UniProt: A0A0M3KL26)
| PDB | External Database | Details |
|---|---|---|
| Gln 153 | Glu 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136654.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1345.9 | |
| All* | Total formula weight | 138000.7 |
