5TNG
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 14,15-EpETE hydrolysis intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CFTR inhibitory factor | polymer | 301 | 34163.7 | 4 | UniProt (A0A0M3KL26) UniProt (by SIFTS) (A0A0H2ZD27) | Pseudomonas aeruginosa (strain UCBPP-PA14) | |
| 2 | E, F, G, H (A, B, C, D) | (5Z,8Z,11Z,14R,15R,17Z)-14,15-dihydroxyicosa-5,8,11,17-tetraenoic acid | non-polymer | 336.5 | 4 | Chemie (7LE) PubChem (177598701) PubChem (35026840) PubChem (35026846) PubChem (35026852) PubChem (35026859) PubChem (53394516) PubChem (16061119) PubChem (131704446) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1231 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 25 - 325 (UniProt: A0A0M3KL26)
| PDB | External Database | Details |
|---|---|---|
| Gln 153 | Glu 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136654.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1345.9 | |
| All* | Total formula weight | 138000.7 |
