5TND
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxycyclohexane hydrolysis intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, D, A, B) | CFTR inhibitory factor | polymer | 301 | 34163.7 | 4 | UniProt (A0A0M3KL26) Pfam (PF12697) UniProt (by SIFTS) (A0A0H2ZD27) | Pseudomonas aeruginosa (strain UCBPP-PA14) | |
| 2 | E, G, I, K (C, D, A, B) | (1R,2R)-cyclohexane-1,2-diol | non-polymer | 116.2 | 4 | Chemie (40O) | |||
| 3 | F, H, J, L (C, D, A, B) | (1S,2S)-cyclohexane-1,2-diol | non-polymer | 116.2 | 4 | Chemie (3ZQ) | |||
| 4 | M, N, O, P (C, D, A, B) | water | water | 18.0 | 1211 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 25 - 325 (UniProt: A0A0M3KL26)
| PDB | External Database | Details |
|---|---|---|
| Gln 153 | Glu 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136654.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 929.3 | |
| All* | Total formula weight | 137584.1 |
