5TLS
2.4 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with DZ2002 and NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 498 | 56200.7 | 4 | UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) | Cryptosporidium parvum (strain Iowa II) | |
| 2 | AA, E, M, S (D, A, B, C) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | BA, F, N, T (D, A, B, C) | (2S)-4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoic acid | non-polymer | 237.2 | 4 | Chemie (ZD2) | |||
| 4 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | CA, DA, EA, FA, H... (D, A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 17 | Chemie (PO4) | |||
| 6 | O, U (B, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 1036 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 495 (UniProt: Q5CPH1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224802.7 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 5436.7 | |
| All* | Total formula weight | 230239.4 |
