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5TK5

Crystal structure of human 3HAO with iron bound in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3-hydroxyanthranilate 3,4-dioxygenasepolymer29032892.41UniProt (P46952)
Pfam (PF06052)
Homo sapiens (Human)3-hydroxyanthranilate oxygenase,3-HAO,3-hydroxyanthranilic acid dioxygenase,HAD
2B
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
3C, D, E
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
4F
(A)
waterwater18.0173Chemie (HOH)
Sequence modifications
A: 1 - 286 (UniProt: P46952)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32892.4
Non-Polymers*Number of molecules4
Total formula weight344.0
All*Total formula weight33236.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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