5TJG
Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-directed RNA polymerase subunit alpha | polymer | 314 | 34929.1 | 2 | UniProt (Q9KWU8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Thermus aquaticus | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C | DNA-directed RNA polymerase subunit beta | polymer | 1119 | 124930.0 | 1 | UniProt (Q9KWU7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Thermus aquaticus | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D | DNA-directed RNA polymerase subunit beta' | polymer | 1524 | 171153.5 | 1 | UniProt (Q9KWU6) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Thermus aquaticus | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E | DNA-directed RNA polymerase subunit omega | polymer | 99 | 11642.4 | 1 | UniProt (Q9EVV4) Pfam (PF01192) In PDB | Thermus aquaticus | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F | RNA polymerase sigma factor SigA | polymer | 347 | 39864.7 | 1 | UniProt (Q9EZJ8) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) In PDB | Thermus aquaticus | |
| 6 | G | DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3') | polymer | 31 | 9682.2 | 1 | Escherichia coli | ||
| 7 | D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 8 | D | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 314 (UniProt: Q9KWU8)
D: 1 - 1524 (UniProt: Q9KWU6)
| PDB | External Database | Details |
|---|---|---|
| Arg 14 | Thr 14 | conflict |
| Arg 18 | Asp 18 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ile 666 | Phe 666 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 427131.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 427286.2 |
