5TIL

Murine class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell receptor P14

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	H-2 class I histocompatibility antigen, D-B alpha chain	polymer	276	32087.7	2	UniProt (P01899) Pfam (PF00129) Pfam (PF07654)	Mus musculus (Mouse)	H-2D(B)
2	B, E (B, E)	Beta-2-microglobulin	polymer	99	11704.4	2	UniProt (P01887) Pfam (PF07654)	Mus musculus (Mouse)
3	C, F (C, F)	Pre-glycoprotein polyprotein GP complex	polymer	9	1043.2	2	UniProt (Q9QDK7)	Lymphocytic choriomeningitis mammarenavirus
4	G (G)	alpha chain of P14 T cell receptor	polymer	205	23072.7	1		Mus musculus (Mouse)
5	H, J (H, L)	Beta chain of murine T cell receptor P14	polymer	238	26647.6	2		Mus musculus (Mouse)
6	I (K)	Alpha chain of murine P14 T cell receptor	polymer	160	18090.1	1		Mus musculus (Mouse)
7	K, L, M, N, O... (A, B, D, E, G...)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

B, E: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Asp 85	Ala 105	variant

C, F: 1 - 9 (UniProt: Q9QDK7)

PDB	External Database	Details
Pro 3	Val 35	engineered mutation
Met 9	Cys 41	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	184128.6
All*	Total formula weight	184128.6

*Water molecules are not included.