5THM

Esterase-6 from Drosophila melanogaster

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Esterase-6	polymer	533	60913.8	1	UniProt (P08171) Pfam (PF00135) In PDB	Drosophila melanogaster (Fruit fly)	Est-6,Carboxylic-ester hydrolase 6,Carboxylesterase-6
2	A	N,N-dimethylboranamine	non-polymer		56.9	1	Chemie (7BZ)
3		water	water		18.0	322	Chemie (HOH)

Sequence modifications

A: 1 - 523 (UniProt: P08171)

PDB	External Database	Details
Met -9	-	initiating methionine
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Asp -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Val 15	Lys 36	engineered mutation
Leu 145	Val 166	engineered mutation
Mly 208	Arg 229	engineered mutation
Glu 229	Gly 250	engineered mutation
Ser 237	Asn 258	engineered mutation
Ala 247	Thr 268	engineered mutation
Gly 290	Asp 311	engineered mutation
Phe 292	Ile 313	engineered mutation
Val 335	Ile 356	engineered mutation
Gly 383	Glu 404	engineered mutation
Gly 400	Ser 421	engineered mutation
Val 416	Ala 437	engineered mutation
Ser 450	Phe 471	engineered mutation
Ser 456	Phe 477	engineered mutation
Asp 485	Asn 506	engineered mutation
Thr 511	Ile 532	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	60913.8
Non-Polymers*	Number of molecules	1
	Total formula weight	56.9
All*	Total formula weight	60970.7

*Water molecules are not included.