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5THL

Crystal structure of the human tyrosyl-tRNA synthetase mutant G41R

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine--tRNA ligase, cytoplasmicpolymer37242233.71UniProt (P54577)
Pfam (PF00579)
Homo sapiens (Human)Tyrosyl-tRNA synthetase,TyrRS
2B
(A)
waterwater18.0387Chemie (HOH)
Sequence modifications
A: 1 - 364 (UniProt: P54577)
PDBExternal DatabaseDetails
Arg 41Gly 41engineered mutation
Leu 365-expression tag
Glu 366-expression tag
His 367-expression tag
His 368-expression tag
His 369-expression tag
His 370-expression tag
His 371-expression tag
His 372-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42233.7
All*Total formula weight42233.7
*Water molecules are not included.

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PDB entries from 2025-12-17

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