5TG1
1.40 A resolution structure of Norovirus 3CL protease in complex with the a m-chlorophenyl substituted macrocyclic inhibitor (17-mer)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 3C-LIKE PROTEASE | polymer | 188 | 20126.1 | 1 | UniProt (Q83883) In PDB | Norwalk virus (Hu/NV/NV/1968/US) | |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | A | (4S,7S,17S)-17-(3-chlorophenyl)-7-(hydroxymethyl)-4-(2-methylpropyl)-1-oxa-3,6,11-triazacycloheptadecane-2,5,10-trione | non-polymer | 482.0 | 1 | BIRD (PRD_002249) Chemie (V56) | |||
| 4 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: Q83883)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20126.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 552.9 | |
| All* | Total formula weight | 20679.1 |
