5TFO
CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE with a deletion V76-L86 in NS2b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NS2B-NS3 Protease CHIMERA,NS2B-NS3 PROTEASE,NS2B-NS3 Protease CHIMERA | polymer | 232 | 24508.3 | 2 | UniProt (Q32ZE1) Pfam (PF01002) Pfam (PF00949) In PDB | Zika virus (ZIKV) | |
| 2 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B: 48 - 75 (UniProt: Q32ZE1)
A, B: 78 - 85 (PDB: 5TFO)
A, B: 1001 - 1182 (UniProt: Q32ZE1)
| PDB | External Database | Details |
|---|---|---|
| Gly 46 | - | expression tag |
| Ser 47 | - | expression tag |
A, B: 1001 - 1182 (UniProt: Q32ZE1)
| PDB | External Database | Details |
|---|---|---|
| Gly 76 | - | insertion |
| Gly 77 | - | insertion |
| Ala 86 | - | linker |
| Gly 87 | - | linker |
| Gly 88 | - | linker |
| Gly 89 | - | linker |
| Gly 90 | - | linker |
| Ser 91 | - | linker |
| Gly 92 | - | linker |
| Gly 93 | - | linker |
| Gly 94 | - | linker |
| Gly 95 | - | linker |
| Ser 1056 | Ala 1554 | conflict |
| His 1092 | Leu 1590 | conflict |
| Arg 1169 | Lys 1667 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49016.6 | |
| All* | Total formula weight | 49016.6 |
