5TFO

CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE with a deletion V76-L86 in NS2b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NS2B-NS3 Protease CHIMERA,NS2B-NS3 PROTEASE,NS2B-NS3 Protease CHIMERA	polymer	232	24508.3	2	UniProt (Q32ZE1) Pfam (PF01002) Pfam (PF00949)	Zika virus (ZIKV)
2	C, D (A, B)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 48 - 75 (UniProt: Q32ZE1)

PDB	External Database	Details
Gly 46	-	expression tag
Ser 47	-	expression tag

A, B: 78 - 85 (PDB: 5TFO)
A, B: 1001 - 1182 (UniProt: Q32ZE1)

PDB	External Database	Details
Gly 76	-	insertion
Gly 77	-	insertion
Ala 86	-	linker
Gly 87	-	linker
Gly 88	-	linker
Gly 89	-	linker
Gly 90	-	linker
Ser 91	-	linker
Gly 92	-	linker
Gly 93	-	linker
Gly 94	-	linker
Gly 95	-	linker
Ser 1056	Ala 1554	conflict
His 1092	Leu 1590	conflict
Arg 1169	Lys 1667	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49016.6
All*	Total formula weight	49016.6

*Water molecules are not included.