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5TDP

Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
anti-HER2 Fab Light Chainpolymer21423385.02Homo sapiens
2B, D
(B, D)
anti-HER2 Fab Heavy Chainpolymer22323727.62Homo sapiens
3E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4F, G, H, I
(A, B, C, D)
waterwater18.0479Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight94225.3
Non-Polymers*Number of molecules1
Total formula weight92.1
All*Total formula weight94317.4
*Water molecules are not included.

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PDB entries from 2025-12-17

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