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5TDO

Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
anti-HER2 Fab Light Chainpolymer21423463.02Homo sapiens
2B, D
(B, D)
anti-HER2 Fab Heavy Chainpolymer22323787.72Homo sapiens
3E, F, G
(A, B, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
4H, I, J, K
(A, B, C, D)
waterwater18.0453Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight94501.3
Non-Polymers*Number of molecules3
Total formula weight276.3
All*Total formula weight94777.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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