5TDE

TEV Cleaved Human ATP Citrate Lyase Bound to Citrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATP-citrate synthase	polymer	431	47836.6	1	UniProt (P53396) Pfam (PF16114) In PDB	Homo sapiens (Human)	ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme
2	B	ATP-citrate synthase	polymer	324	35342.6	1	UniProt (P53396) Pfam (PF02629) Pfam (PF00549) In PDB	Homo sapiens (Human)	ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme
3	A	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)
4	A, B	DIHYDROGENPHOSPHATE ION	non-polymer		97.0	3	Chemie (2HP)
5	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
6	A, B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
7		water	water		18.0	737	Chemie (HOH)

Sequence modifications

A: 1 - 425 (UniProt: P53396)

PDB	External Database	Details
Glu 426	-	SEE REMARK 999
Asn 427	-	SEE REMARK 999
Leu 428	-	SEE REMARK 999
Tyr 429	-	SEE REMARK 999
Phe 430	-	SEE REMARK 999
Gln 431	-	SEE REMARK 999

B: 488 - 810 (UniProt: P53396)

PDB	External Database	Details
Ser 487	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83179.2
Non-Polymers*	Number of molecules	10
	Total formula weight	894.4
All*	Total formula weight	84073.6

*Water molecules are not included.