5TCF
Crystal structure of tryptophan synthase from M. tuberculosis - ligand-free form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, G, E, C) | Tryptophan synthase alpha chain | polymer | 276 | 28579.4 | 4 | UniProt (P9WFY1) Pfam (PF00290) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | B, D, F, H (B, H, F, D) | Tryptophan synthase beta chain | polymer | 410 | 43562.7 | 4 | UniProt (P9WFX9) Pfam (PF00291) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 3 | BA, I, Q, W (C, A, G, E) | MALONATE ION | non-polymer | 102.0 | 4 | Chemie (MLI) | |||
| 4 | AA, CA, DA, EA, FA... (F, C, D, A, B...) | FORMIC ACID | non-polymer | 46.0 | 21 | Chemie (FMT) | |||
| 5 | O, P, V (B, H) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 6 | KA, LA, MA, NA, OA... (A, B, G, H, E...) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, G, E, C: 1 - 270 (UniProt: P9WFY1)
| PDB | External Database | Details |
|---|---|---|
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 288568.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 1492.0 | |
| All* | Total formula weight | 290060.6 |
