5TC7
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with 5'-methylthiotubercidin at 1.75 angstrom
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S-methyl-5'-thioadenosine phosphorylase | polymer | 297 | 33119.1 | 1 | UniProt (Q13126) Pfam (PF01048) In PDB | Homo sapiens (Human) | 5'-methylthioadenosine phosphorylase,MTAPase |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
3 | A | 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL | non-polymer | 296.3 | 1 | Chemie (MTH) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 1 - 283 (UniProt: Q13126)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33119.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 616.7 | |
All* | Total formula weight | 33735.8 |