5TB6
Structure of bromodomain of CREBBP with a pyrazolo[4,3-c]pyridin fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREB-binding protein | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | B (A) | 1-(3-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)propan-1-one | non-polymer | 255.3 | 1 | Chemie (77X) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14223.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 317.4 | |
| All* | Total formula weight | 14540.7 |
