5TAR
Crystal structure of farnesylated and methylated kras4b in complex with PDE-delta (crystal form II - with ordered hypervariable region)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 185 | 21056.0 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (B) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 148 | 17222.7 | 1 | UniProt (O43924) Pfam (PF05351) | Homo sapiens (Human) | GMP-PDE delta,Protein p17 |
| 3 | C (A) | FARNESYL | non-polymer | 206.4 | 1 | Chemie (FAR) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 2 - 185 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38278.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 711.6 | |
| All* | Total formula weight | 38990.4 |
