5T6C
Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a dichloro-methylpyridinyl-methoxy-phenyl-pyridine piperazine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycylpeptide N-tetradecanoyltransferase | polymer | 411 | 47443.3 | 1 | UniProt (Q9UVX3) Pfam (PF01233) Pfam (PF02799) | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | Myristoyl-CoA:protein N-myristoyltransferase,NMT,Peptide N-myristoyltransferase |
| 2 | B (A) | TETRADECANOYL-COA | non-polymer | 977.9 | 1 | Chemie (MYA) | |||
| 3 | C (A) | 1-(4-{3,5-dichloro-4-[(2-methylpyridin-3-yl)methoxy]phenyl}pyridin-2-yl)piperazine | non-polymer | 429.3 | 1 | Chemie (75S) | |||
| 4 | D (A) | water | water | 18.0 | 502 | Chemie (HOH) |
Sequence modifications
A: 86 - 492 (UniProt: Q9UVX3)
| PDB | External Database | Details |
|---|---|---|
| Gly 82 | - | expression tag |
| Pro 83 | - | expression tag |
| Arg 84 | - | expression tag |
| Ser 85 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47443.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1407.2 | |
| All* | Total formula weight | 48850.5 |
