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5SYG

Cryo-EM reconstruction of zampanolide-bound microtubule

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tubulin alpha chainpolymer43748679.11UniProt (B6A7R0)
Pfam (PF00091)
Pfam (PF03953)
UniProt (by SIFTS) (Q2XVP4)
Sus scrofa (Pig)
2B
(B)
Tubulin beta chainpolymer42647825.91UniProt (P02554)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (Pig)Beta-tubulin
3C
(A)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E
(B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
6F
(B)
(2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamidenon-polymer497.61Chemie (ZPN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight96504.9
Non-Polymers*Number of molecules4
Total formula weight1488.3
All*Total formula weight97993.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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