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5SK8

Crystal Structure of human phosphodiesterase 10 in complex with 4-chloro-N-(2-phenyl-1H-benzimidazol-5-yl)-2-propylpyrazole-3-carboxamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Apolymer34339489.31UniProt (Q9Y233)
In PDB
Homo sapiens (human)
2AZINC IONnon-polymer65.41Chemie (ZN)
3AMAGNESIUM IONnon-polymer24.31Chemie (MG)
4A4-chloro-N-(2-phenyl-1H-benzimidazol-5-yl)-1-propyl-1H-pyrazole-5-carboxamidenon-polymer379.81Chemie (KCU)
5waterwater18.0147Chemie (HOH)
Sequence modifications
A: 449 - 789 (UniProt: Q9Y233)
PDBExternal DatabaseDetails
Gly 447-expression tag
Ser 448-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39489.3
Non-Polymers*Number of molecules3
Total formula weight469.6
All*Total formula weight39958.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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