5SCC
Structure of liver pyruvate kinase in complex with anthraquinone derivative 57
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pyruvate kinase | polymer | 447 | 48285.4 | 8 | UniProt (Q16716) Pfam (PF00224) Pfam (PF02887) UniProt (by SIFTS) (P30613) | Homo sapiens (human) | |
| 2 | DA, I, IA, M, NA... (F, A, G, B, H...) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 8 | Chemie (FBP) PubChem (718) PubChem (10267) PubChem (172313) PubChem (440117) PubChem (5702629) PubChem (12800340) PubChem (16219368) PubChem (24802138) PubChem (46937007) PubChem (445557) PubChem (92209487) PubChem (124383956) PubChem (124540446) PubChem (135053794) PubChem (89534552) PubChem (92209485) PubChem (92209486) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 3 | AA, EA, J, JA, N... (E, F, A, G, B...) | OXALATE ION | non-polymer | 88.0 | 8 | Chemie (OXL) PubChem (71081) | |||
| 4 | BA, GA, K, LA, O... (E, F, A, G, B...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 5 | CA, HA, L, MA, P... (E, F, A, G, B...) | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) PubChem (813) | |||
| 6 | FA, KA, S (F, G, C) | 4-amino-3-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid | non-polymer | 319.3 | 3 | Chemie (I8Q) PubChem (129639897) | |||
| 7 | RA, SA, TA, UA, VA... (A, B, C, D, E...) | water | water | 18.0 | 2332 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 129 (UniProt: Q16716)
A, B, C, D, E, F, G, H: 231 - 543 (UniProt: Q16716)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 12 | Ser 35 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | - | linker |
| Ser 131 | - | linker |
| Gly 132 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 386283.0 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 4890.2 | |
| All* | Total formula weight | 391173.2 |
