5SAX
DDR1, 2-[3-(2-pyridin-3-ylethynyl)phenyl]-N-[3-(trifluoromethyl)phenyl]acetamide, 1.902A, second P212121 form, Rfree=25.4%, second form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epithelial discoidin domain-containing receptor 1 | polymer | 321 | 36502.9 | 1 | UniProt (Q08345) Pfam (PF07714) | Homo sapiens (Human) | Epithelial discoidin domain receptor 1,CD167 antigen-like family member A,Cell adhesion kinase,Discoidin receptor tyrosine kinase,HGK2,Mammary carcinoma kinase 10,MCK-10,Protein-tyrosine kinase 3A,Protein-tyrosine kinase RTK-6,TRK E,Tyrosine kinase DDR,Tyrosine-protein kinase CAK |
| 2 | B, C, D, E, F... (A) | IODIDE ION | non-polymer | 126.9 | 8 | Chemie (IOD) | |||
| 3 | J (A) | 2-{3-[(pyridin-3-yl)ethynyl]phenyl}-N-[3-(trifluoromethyl)phenyl]acetamide | non-polymer | 380.4 | 1 | Chemie (1IM) | |||
| 4 | K (A) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 593 - 907 (UniProt: Q08345)
| PDB | External Database | Details |
|---|---|---|
| - | Gly 730 | deletion |
| - | Gln 731 | deletion |
| - | Ala 732 | deletion |
| - | Ala 733 | deletion |
| - | Gln 734 | deletion |
| - | Gly 735 | deletion |
| His 908 | - | expression tag |
| His 909 | - | expression tag |
| His 910 | - | expression tag |
| His 911 | - | expression tag |
| His 912 | - | expression tag |
| His 913 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36502.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1395.6 | |
| All* | Total formula weight | 37898.5 |
