5S8P
XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with E07179c (space group P212121)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PH-interacting protein | polymer | 128 | 15156.2 | 2 | UniProt (Q8WWQ0) Pfam (PF00439) | Homo sapiens (Human) | PHIP,DDB1- and CUL4-associated factor 14,IRS-1 PH domain-binding protein,WD repeat-containing protein 11 |
| 2 | C (A) | 3-methyl-3,4-dihydroquinazolin-2(1H)-one | non-polymer | 162.2 | 1 | Chemie (3PF) | |||
| 3 | D, E (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | F, G, H, I, J... (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A, B: 1315 - 1440 (UniProt: Q8WWQ0)
| PDB | External Database | Details |
|---|---|---|
| Ser 1313 | - | expression tag |
| Met 1314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30312.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 614.8 | |
| All* | Total formula weight | 30927.1 |
