5RXA
INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z2856434829
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | polymer | 463 | 52877.6 | 1 | UniProt (Q92835) Pfam (PF22669) | Homo sapiens (human) | Inositol polyphosphate-5-phosphatase D,Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship,hp51CN |
| 2 | B, C (A) | [3,4-bis(fluoranyl)phenyl]-(4-methylpiperazin-1-yl)methanone | non-polymer | 240.2 | 2 | Chemie (ELQ) | |||
| 3 | D, E, F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 4 | G (A) | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
A: 396 - 856 (UniProt: Q92835)
| PDB | External Database | Details |
|---|---|---|
| Ser 394 | - | expression tag |
| Met 395 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52877.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 714.9 | |
| All* | Total formula weight | 53592.5 |
