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5RX3

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1262327505

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1polymer46352877.61UniProt (Q92835)
In PDB
Homo sapiens (human)Inositol polyphosphate-5-phosphatase D,Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship,hp51CN
2AN-{[(3R)-pyrrolidin-3-yl]methyl}pyridin-2-aminenon-polymer177.21Chemie (WNJ)
3ADIMETHYL SULFOXIDEnon-polymer78.13Chemie (DMS)
4waterwater18.0445Chemie (HOH)
Sequence modifications
A: 396 - 856 (UniProt: Q92835)
PDBExternal DatabaseDetails
Ser 394-expression tag
Met 395-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52877.6
Non-Polymers*Number of molecules4
Total formula weight411.6
All*Total formula weight53289.2
*Water molecules are not included.

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PDB entries from 2024-06-12

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