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5RX0

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z57258487

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1polymer46352877.61UniProt (Q92835)
In PDB
Homo sapiens (human)Inositol polyphosphate-5-phosphatase D,Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship,hp51CN
2AN-{[4-(dimethylamino)phenyl]methyl}-4H-1,2,4-triazol-4-aminenon-polymer217.31Chemie (NVD)
3ADIMETHYL SULFOXIDEnon-polymer78.13Chemie (DMS)
4APHOSPHATE IONnon-polymer95.01Chemie (PO4)
5AMAGNESIUM IONnon-polymer24.31Chemie (MG)
6waterwater18.0437Chemie (HOH)
Sequence modifications
A: 396 - 856 (UniProt: Q92835)
PDBExternal DatabaseDetails
Ser 394-expression tag
Met 395-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52877.6
Non-Polymers*Number of molecules6
Total formula weight570.9
All*Total formula weight53448.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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