5RWH
INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1152242726
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | polymer | 463 | 52877.6 | 1 | UniProt (Q92835) Pfam (PF22669) In PDB | Homo sapiens (human) | Inositol polyphosphate-5-phosphatase D,Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship,hp51CN |
2 | A | N-(6-methoxypyridin-3-yl)-N'-thiophen-2-ylurea | non-polymer | 249.3 | 1 | Chemie (VZM) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
4 | water | water | 18.0 | 434 | Chemie (HOH) |
Sequence modifications
A: 396 - 856 (UniProt: Q92835)
PDB | External Database | Details |
---|---|---|
Ser 394 | - | expression tag |
Met 395 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 52877.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 483.7 | |
All* | Total formula weight | 53361.3 |