5RVX
PanDDA analysis group deposition -- Crystal Structure of DHTKD1 in complex with Z804566442
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial | polymer | 898 | 100926.1 | 2 | UniProt (Q96HY7) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | Homo sapiens (Human) | Dehydrogenase E1 and transketolase domain-containing protein 1 |
| 2 | C, G (A, B) | 5-ethyl-~{N}-[(1-methylpyrazol-4-yl)methyl]thiophene-2-carboxamide | non-polymer | 249.3 | 2 | Chemie (B0Y) | |||
| 3 | D, H (A, B) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
| 4 | E, F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 1800 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 919 (UniProt: Q96HY7)
| PDB | External Database | Details |
|---|---|---|
| Met 22 | - | initiating methionine |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Gly 31 | - | expression tag |
| Val 32 | - | expression tag |
| Asp 33 | - | expression tag |
| Leu 34 | - | expression tag |
| Gly 35 | - | expression tag |
| Thr 36 | - | expression tag |
| Glu 37 | - | expression tag |
| Asn 38 | - | expression tag |
| Leu 39 | - | expression tag |
| Tyr 40 | - | expression tag |
| Phe 41 | - | expression tag |
| Gln 42 | - | expression tag |
| Ser 43 | - | expression tag |
| Met 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 201852.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1422.2 | |
| All* | Total formula weight | 203274.4 |
