5RKF

PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1674937530

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PH-interacting protein	polymer	149	17627.9	1	UniProt (Q8WWQ0) Pfam (PF00439)	Homo sapiens (Human)	PHIP,DDB1- and CUL4-associated factor 14,IRS-1 PH domain-binding protein,WD repeat-containing protein 11
2	B (A)	2-(1-ethyl-1H-pyrazol-4-yl)ethan-1-ol	non-polymer		140.2	1	Chemie (UVY)
3	C (A)	water	water		18.0	232	Chemie (HOH)

Sequence modifications

A: 1315 - 1440 (UniProt: Q8WWQ0)

PDB	External Database	Details
Met 1292	-	initiating methionine
His 1293	-	expression tag
His 1294	-	expression tag
His 1295	-	expression tag
His 1296	-	expression tag
His 1297	-	expression tag
His 1298	-	expression tag
Ser 1299	-	expression tag
Ser 1300	-	expression tag
Gly 1301	-	expression tag
Val 1302	-	expression tag
Asp 1303	-	expression tag
Leu 1304	-	expression tag
Gly 1305	-	expression tag
Thr 1306	-	expression tag
Glu 1307	-	expression tag
Asn 1308	-	expression tag
Leu 1309	-	expression tag
Tyr 1310	-	expression tag
Phe 1311	-	expression tag
Gln 1312	-	expression tag
Ser 1313	-	expression tag
Met 1314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17627.9
Non-Polymers*	Number of molecules	1
	Total formula weight	140.2
All*	Total formula weight	17768.0

*Water molecules are not included.