5REQ
Methylmalonyl-COA MUTASE, Y89F Mutant, substrate complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | PROTEIN (METHYLMALONYL-COA MUTASE ALPHA-SUBUNIT) | polymer | 727 | 80121.9 | 2 | UniProt (P11653) Pfam (PF01642) Pfam (PF02310) In PDB | Propionibacterium freudenreichii subsp. shermanii | |
2 | B, D | PROTEIN (METHYLMALONYL-COA MUTASE BETA-SUBUNIT) | polymer | 637 | 69430.2 | 2 | UniProt (P11652) Pfam (PF01642) In PDB | Propionibacterium freudenreichii subsp. shermanii | |
3 | A, C | SUCCINYL(CARBADETHIA)-COENZYME A | non-polymer | 849.6 | 2 | Chemie (SCD) | |||
4 | A, C | METHYLMALONYL(CARBADETHIA)-COENZYME A | non-polymer | 849.6 | 2 | Chemie (MCD) | |||
5 | A, C | COBALAMIN | non-polymer | 1330.4 | 2 | Chemie (B12) | |||
6 | B, D | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
7 | water | water | 18.0 | 1094 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 728 (UniProt: P11653)
B, D: 2 - 638 (UniProt: P11652)
PDB | External Database | Details |
---|---|---|
Phe 89 | Tyr 89 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 203 | Ala 203 | SEE REMARK 999 |
Glu 330 | Asp 330 | SEE REMARK 999 |
Leu 331 | Val 331 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 299104.1 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 6427.4 | |
All* | Total formula weight | 305531.4 |