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5R66

PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with FMOPL000198a

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cleavage and polyadenylation specificity factor subunit 5polymer19722874.42UniProt (O43809)
Pfam (PF13869)
Homo sapiens (Human)Cleavage and polyadenylation specificity factor 25 kDa subunit,CPSF 25 kDa subunit,Cleavage factor Im complex 25 kDa subunit,CFIm25,Nucleoside diphosphate-linked moiety X motif 21,Nudix motif 21,Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit
2C, D, G, H, I...
(A, B)
ZINC IONnon-polymer65.46Chemie (ZN)
3E, F
(A)
ACETATE IONnon-polymer59.02Chemie (ACT)
4K
(B)
N-(2,3-dimethylphenyl)-2-(morpholin-4-yl)acetamidenon-polymer248.31Chemie (NT7)
5L, M
(A, B)
waterwater18.0251Chemie (HOH)
Sequence modifications
A, B: 33 - 227 (UniProt: O43809)
PDBExternal DatabaseDetails
Ser 31-expression tag
Met 32-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45748.8
Non-Polymers*Number of molecules9
Total formula weight758.9
All*Total formula weight46507.6
*Water molecules are not included.

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PDB entries from 2025-08-27

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