5R4V
XChem fragment screen -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF THE HUMAN ATAD2 in complex with N13475a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ATPase family AAA domain-containing protein 2 | polymer | 130 | 15512.6 | 1 | UniProt (Q6PL18) Pfam (PF00439) In PDB | Homo sapiens (Human) | AAA nuclear coregulator cancer-associated protein,ANCCA |
2 | A | [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone | non-polymer | 248.3 | 2 | Chemie (JMM) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
PDB | External Database | Details |
---|---|---|
Ser 979 | - | expression tag |
Met 980 | - | expression tag |
Arg 1022 | Val 1022 | conflict |
Glu 1027 | Gln 1027 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15512.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 874.9 | |
All* | Total formula weight | 16387.4 |