5R4S
PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with EN08775-45
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cleavage and polyadenylation specificity factor subunit 5 | polymer | 197 | 22874.4 | 2 | UniProt (O43809) Pfam (PF13869) In PDB | Homo sapiens (Human) | Cleavage and polyadenylation specificity factor 25 kDa subunit,CPSF 25 kDa subunit,Cleavage factor Im complex 25 kDa subunit,CFIm25,Nucleoside diphosphate-linked moiety X motif 21,Nudix motif 21,Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit |
| 2 | A | (4S,5R)-4-hydroxy-5-methyl-5-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]pyrrolidin-2-one | non-polymer | 272.3 | 1 | Chemie (RWD) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | A, B | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 227 (UniProt: O43809)
| PDB | External Database | Details |
|---|---|---|
| Ser 31 | - | expression tag |
| Met 32 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45748.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 841.9 | |
| All* | Total formula weight | 46590.7 |
