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5R4P

PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with NM450-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCleavage and polyadenylation specificity factor subunit 5polymer19722874.42UniProt (O43809)
Pfam (PF13869)
In PDB
Homo sapiens (Human)Cleavage and polyadenylation specificity factor 25 kDa subunit,CPSF 25 kDa subunit,Cleavage factor Im complex 25 kDa subunit,CFIm25,Nucleoside diphosphate-linked moiety X motif 21,Nudix motif 21,Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit
2A, BZINC IONnon-polymer65.46Chemie (ZN)
3AACETATE IONnon-polymer59.01Chemie (ACT)
4A(5S)-5-methyl-5-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]pyrrolidine-2,4-dionenon-polymer270.31Chemie (RVY)
5waterwater18.0255Chemie (HOH)
Sequence modifications
A, B: 33 - 227 (UniProt: O43809)
PDBExternal DatabaseDetails
Ser 31-expression tag
Met 32-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45748.8
Non-Polymers*Number of molecules8
Total formula weight721.8
All*Total formula weight46470.6
*Water molecules are not included.

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PDB entries from 2024-08-21

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