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5R4P

PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with NM450-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cleavage and polyadenylation specificity factor subunit 5polymer19722874.42UniProt (O43809)
Pfam (PF13869)
Homo sapiens (Human)Cleavage and polyadenylation specificity factor 25 kDa subunit,CPSF 25 kDa subunit,Cleavage factor Im complex 25 kDa subunit,CFIm25,Nucleoside diphosphate-linked moiety X motif 21,Nudix motif 21,Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit
2C, D, G, H, I...
(A, B)
ZINC IONnon-polymer65.46Chemie (ZN)
3E
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4F
(A)
(5S)-5-methyl-5-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]pyrrolidine-2,4-dionenon-polymer270.31Chemie (RVY)
5K, L
(A, B)
waterwater18.0255Chemie (HOH)
Sequence modifications
A, B: 33 - 227 (UniProt: O43809)
PDBExternal DatabaseDetails
Ser 31-expression tag
Met 32-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45748.8
Non-Polymers*Number of molecules8
Total formula weight721.8
All*Total formula weight46470.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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