5QTP
PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with AE-0227
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ADP-sugar pyrophosphatase | polymer | 209 | 23136.1 | 4 | UniProt (Q9UKK9) Pfam (PF00293) | Homo sapiens (Human) | 8-oxo-dGDP phosphatase, Nuclear ATP-synthesis protein NUDIX5, Nucleoside diphosphate-linked moiety X motif 5, hNUDT5, YSA1H |
| 2 | E, F, L, M, Q... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 3 | G, N, U, V (A, B, C, D) | 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carbonitrile | non-polymer | 245.6 | 4 | Chemie (PWJ) | |||
| 4 | H, I, K, O, P... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | J (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 208 (UniProt: Q9UKK9)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92544.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1708.8 | |
| All* | Total formula weight | 94253.1 |
