5QT0
PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z321318226
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T-box transcription factor T | polymer | 172 | 19655.6 | 1 | UniProt (O15178) Pfam (PF00907) | Homo sapiens (Human) | Brachyury protein,Protein T |
| 2 | B (A) | N-(4-methoxyphenyl)-N'-pyridin-4-ylurea | non-polymer | 243.3 | 1 | Chemie (JHJ) | |||
| 3 | C (A) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A: 41 - 211 (UniProt: O15178)
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Asp 177 | Gly 177 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19655.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 243.3 | |
| All* | Total formula weight | 19898.9 |
