5QG4
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000666a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37345.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
2 | A | methyl (1S,3S,4R)-4-hydroxy-3-[(1S)-1-hydroxypropyl]-2-azabicyclo[2.2.2]octane-2-carboxylate | non-polymer | 243.3 | 1 | Chemie (JPD) | |||
3 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
4 | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
PDB | External Database | Details |
---|---|---|
Ser 32 | Cys 32 | engineered mutation |
Val 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37345.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 365.4 | |
All* | Total formula weight | 37711.0 |