5QFM
PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOMB000269a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37345.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
2 | A | N-[(1R,2S,4S)-bicyclo[2.2.1]heptan-2-yl]-N'-[(2R)-2-hydroxypropyl]thiourea | non-polymer | 228.4 | 1 | Chemie (JOP) | |||
3 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
4 | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
PDB | External Database | Details |
---|---|---|
Ser 32 | Cys 32 | engineered mutation |
Val 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37345.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 350.5 | |
All* | Total formula weight | 37696.1 |