Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cathepsin S | polymer | 223 | 24516.5 | 2 | UniProt (P25774) Pfam (PF00112) | Homo sapiens (Human) | |
| 2 | C, D (A, B) | N-[2-chloro-5-(1-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-6-oxo-1,6-dihydropyrimidin-5-yl)benzyl]-4-fluorobenzamide | non-polymer | 663.6 | 2 | Chemie (N2A) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 217 (UniProt: P25774)
| PDB | External Database | Details |
|---|---|---|
| Ser 25 | Cys 139 | engineered mutation |
| Leu 218 | - | expression tag |
| Gln 219 | - | expression tag |
| Gly 220 | - | expression tag |
| Gly 221 | - | expression tag |
| Gly 222 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49032.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1327.1 | |
| All* | Total formula weight | 50360.1 |
