5Q11
Ligand binding to FARNESOID-X-RECEPTOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bile acid receptor | polymer | 233 | 27100.2 | 1 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
| 2 | B (B) | COACTIVATOR PEPTIDE SRC-1 HD3 | polymer | 14 | 1790.0 | 1 | UniProt (A8K1V4) UniProt (by SIFTS) (Q15788) | Homo sapiens | |
| 3 | C (A) | N,N-dicyclohexyl-3-(2,4-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide | non-polymer | 435.4 | 1 | Chemie (9M7) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 248 - 476 (UniProt: Q96RI1)
| PDB | External Database | Details |
|---|---|---|
| Gly 244 | - | expression tag |
| Ser 245 | - | expression tag |
| His 246 | - | expression tag |
| Met 247 | - | expression tag |
| Ala 281 | Glu 291 | conflict |
| Ala 354 | Glu 364 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28890.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 435.4 | |
| All* | Total formula weight | 29325.6 |
