5Q0A

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-cyanopyrazin-2-yl)-3-[3-(difluoromethoxy)phenyl]sulfonylurea

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, B, C, DFructose-1,6-bisphosphatase 1polymer33836859.44
UniProt (Q2TU34)
Pfam (PF00316)
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
N-[(5-cyanopyrazin-2-yl)carbamoyl]-3-(difluoromethoxy)benzene-1-sulfonamidenon-polymer369.34
waterwater18.0348

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains4
Total molecular weight147437.7
Non-Polymers*Number of molecules4
Total molecular weight1477.2
All*Total molecular weight148914.9
*Water molecules are not included.
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