5Q01
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36859.4 | 8 | UniProt (Q2TU34) Pfam (PF00316) Pfam (PF18913) UniProt (by SIFTS) (P09467) | Homo sapiens (Human) | Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-[(3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy]benzene-1-sulfonamide | non-polymer | 527.2 | 8 | Chemie (95G) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 294875.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4217.6 | |
| All* | Total formula weight | 299092.9 |
