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5PZY

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(2-chlorophenyl)sulfonylurea

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Fructose-1,6-bisphosphatase 1polymer33836859.48UniProt (Q2TU34)
Pfam (PF00316)
Pfam (PF18913)
UniProt (by SIFTS) (P09467)
Homo sapiens (Human)Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
2I, J, K, L, M...
(A, B, C, D, E...)
N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-2-chlorobenzene-1-sulfonamidenon-polymer396.78Chemie (94V)
3Q, R, S, T, U...
(A, B, C, D, E...)
waterwater18.0927Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight294875.3
Non-Polymers*Number of molecules8
Total formula weight3173.3
All*Total formula weight298048.7
*Water molecules are not included.

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PDB entries from 2024-10-30

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