5POC
PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N11081a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain-containing protein 1 | polymer | 156 | 18224.7 | 2 | UniProt (O95696) Pfam (PF00439) In PDB | Homo sapiens (Human) | BR140-like protein,Bromodomain and PHD finger-containing protein 2 |
2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
3 | A | 7-bromo-1-methyl-6-nitroquinolin-2(1H)-one | non-polymer | 283.1 | 1 | Chemie (8TG) | |||
4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 156 (UniProt: O95696)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
Ser 8 | - | expression tag |
Ser 9 | - | expression tag |
Gly 10 | - | expression tag |
Val 11 | - | expression tag |
Asp 12 | - | expression tag |
Leu 13 | - | expression tag |
Gly 14 | - | expression tag |
Thr 15 | - | expression tag |
Glu 16 | - | expression tag |
Asn 17 | - | expression tag |
Leu 18 | - | expression tag |
Tyr 19 | - | expression tag |
Phe 20 | - | expression tag |
Gln 21 | - | expression tag |
Ser 22 | - | expression tag |
Met 23 | Val 555 | engineered mutation |
Glu 34 | Pro 566 | engineered mutation |
Arg 37 | Val 569 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36449.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 554.3 | |
All* | Total formula weight | 37003.7 |